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Antigen discrimination by T cells relies on size-constrained microvillar contact.
Edward Jenkins, Markus Körbel, Caitlin O'Brien-Ball, James McColl, Kevin Y Chen, Mateusz Kotowski, Jane Humphrey, Anna H Lippert, Heather Brouwer, Ana Mafalda Santos, Steven F Lee, Simon J Davis, David Klenerman
Apr 17, 2023
T cells use finger-like protrusions called 'microvilli' to interrogate their targets, but why they do so is unknown. To form contacts, T cells must overcome the highly charged, barrier-like layer of large molecules forming a...
T-Lymphocytes microvilli Receptors Antigen T-Cell Antigens Lymphocyte Activation Signal Transduction
Published by: Nature Communications
John Hewson-a Festschrift
John Hewson
Sep 05, 2013
Dr. John Hewson's appointment to Memorial University's Henrietta Harvey Chair in May 1997 marked 37 years of distinguished service as scholar, teacher and administrator.
Dr. Hewson, an APLA member since the early days of our...
Published by: Atlantic Provinces Linguistic Association
Review of John Haugeland, Dasein Disclosed: John Haugeland’s Heidegger. Ed. Joseph Rouse. Cambridge, Massachusetts
Emily-Jean Gallant
Jan 04, 2019
John Haugeland passed away suddenly in 2010 leaving behind an unfinished book manuscript on Heidegger. He was an analytic philosopher who specialized in the philosophy of mind and cognitive science; however, he had an “extensive...
Published by: Memorial University of Newfoundland
"Dear Folks"
John Benton
Mar 16, 2022
John Benton (M.A. B.Ed. B.A.) is an active scholar and educator. He has published academic articles and books in the philosophy of language, method, and co-authored a book on economics. Benton engages in international outreach...
Published by: Memorial University of Newfoundland
Effects of Frequent Interaction with Non-Native Speakers on English Dialect
Keiko Hirano
Nov 19, 2013
/T,d/ deletion was chosen as a speech token to test modifications to usage by native speakers of English due to frequent interactions with non-native anglophones in Japan. Approximately 250 tokens per each of thirty-nine...
Published by: Atlantic Provinces Linguistic Association
Peter Gratton and John Panteleimon Manoussakis, eds. Traversing the Imaginary: Richard Kearney and the Postmodern Challenge. Evanston, Ill.
Eric Severson
May 04, 2009
Book Review. Eric Severson reviews Peter Gratton and John Panteleimon Manoussakis, eds. Traversing the Imaginary: Richard Kearney and the Postmodern Challenge. Evanston, Ill.: Northwestern University Press, 2007.
Published by: Memorial University of Newfoundland
John Panteleimon Manoussakis, ed. After God: Richard Kearney and the Religious Turn in Continental Philosophy. New York
Eric Severson
May 04, 2009
[Book Review] Eric Severson reviews John Panteleimon Manoussakis, ed. After God: Richard Kearney and the Religious Turn in Continental Philosophy. New York: Fordham University Press, 2005.
Published by: Memorial University of Newfoundland
Modelling the Effects of Chemical Dispersant on the Fate of Spilled Oil
The proposed Energy East pipeline project has raised concerns about potential oil spills in Saint John, New Brunswick, due to increased tanker traffic. While environmental conditions such as strong tide and current could pose...
Quantifying the Lemma Massa as a Proper-Name in the John and Massa Tales
Floyd Knight
Jul 01, 2019
English nouns have been described as having the ability to “switch easily between common-noun and proper-name uses.” Such changes or transformations are sometimes misanalysed by researchers and are often hard for ELL and L2 ESL...
Published by: IGI Global
A Parallel Between Music and Speech
John T. Hogan
Sep 10, 2013
The goal of this paper is to discuss a substantive rather than a formal parallel between language and music and to suggest that musical notation may have value in representing some speech materia!. The domain of interest is...
Published by: Atlantic Provinces Linguistic Association
Influence of Soil Drought Stress on C, N and P Stoichiometry of Tamarix Chinensis Lour. in Yellow River Delta, China
Qiangqiang Rong, Jingtao Liu, Yanpeng Cai, Zhaohua Lu, Zhenzhen Zhao, Wencong Yue, Jiangbao Xia
Aug 04, 2014
Taking the one-year-old T. chinensis (Tamarix chinensis Lour.) in Yellow River Delta as the study object, the variations of C, N and P stoichiometry in T. chinensis under drought stress was studied using pot experiments. The...
Rawls’ Theory of Justice
Laura Dyke
Oct 07, 2014
John Rawls’ theory of justice provided a revolutionary conception of the justice system and the morals behind it. As a solution to the deadlock of utilitarian and intuitionist theories of justice, it presented a superior...
Published by: Memorial University of Newfoundland
Detection and Identification of Microbial Volatile Organic Compounds of the Green Mold Disease
Button mushrooms are one of the most commonly cultivated mushroom species facing different risks e.g.: viral, bacterial and fungal diseases. One of the most common problems is caused by Trichoderma aggressivum, or ‘green mould'...
Environmental Technologies Environmental, Agricultural, and Physical Sciences Environmental Science and Technologies
Published by: IGI Global
Addressing Global Climate Change With Big Data-Driven Urban Planning Policy
John Zacharias
Oct 01, 2021
Cities in China gather data to support strategic and operational management, including databases on buildings, land use, human occupancy, underground services, and travel surveys. However, these data are seldom used to analyze...
Published by: IGI Global
Algonquian Names
Paul Proulx
Sep 05, 2013
Of the many things Algonquianists can be grateful to John Hewson for, perhaps the most useful is his computer-generated dictionary of Proto-Algonquian. And one of the most intriguing reconstructions in it is *e Sinlehk- (with...
Published by: Atlantic Provinces Linguistic Association
The Legacy of John W. Large
Published by: Faculty of Education
C/T Merge Locations for Focus
Virginia Motaoanyane
Sep 10, 2013
Romanian constructions with preverbal focus compared with English clefts point to a parametric approach: languages display different strategies for overt movement to focus according to their parametric setting for [wh/focusl or...
Published by: Atlantic Provinces Linguistic Association
A Looking Forward
Alexandra Gillis
Mar 16, 2022
Alexandra Gillis is a teacher and educational researcher living in the city of Vancouver, on the territorial lands of the Musqueam, Squamish and Tsleil-Waututh peoples, amidst mountains and ocean of Canada’s west coast. She has...
Published by: Memorial University of Newfoundland
Fetishism and Consumer Value
John Branch
Oct 12, 2018
Fetishism is the attribution of value to an object. To understand fetishism, therefore, requires a grasp of the value which is attributed to an object. More dynamically, it points to the need to comprehend the mechanisms—the...
Published by: IGI Global
Poor Public Management and Public Governance Failure
John Ugoani
Jul 01, 2020
Nigeria is regarded as the giant of Africa because of its huge oil resource wealth. For years the country has been restoring peace in troubled countries. It also has the support of world leaders because of its strong advocacy...
Published by: IGI Global
Reward Point Accumulation Behaviour of Credit Card Users in Pune City
Shilly John
Jan 01, 2022
Credit card use is ubiquitous. The credit cardholders’ behaviour of accumulating reward points and its effect is studied. The credit card users are categorised into government employees, private sector employees and the...
Published by: IGI Global
A Review of Transnational Higher Education
John Branch
Jul 20, 2018
The internationalization of higher education is as old as the university itself. Recently, however, there has been a growing interest in transnational higher education, a specific form of internationalization that considers...
Published by: IGI Global
Leveraging on Digital Technologies to Up-Scale Tourism for Economic Growth in Africa
The application of digital technologies in various human endeavours today is unabated. This article presents information and communications technologies (ICTs) as a driving force for promoting tourism in Africa for accelerated...
Business and Management Hospitality, Travel, and Tourism Management Hospitality, Travel, & Tourism Management
Published by: IGI Global
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